Description

[1-(2-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol is a high-value fluorinated organic building block characterized by its unique cyclopropyl and trifluoromethylphenyl structure. This compound matters for its role as a critical intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific stereochemistry and fluorine content are essential for bioactivity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of fluorinated monomers or polymers for specialty materials with unique surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and enzyme mechanisms.

Basic Information

Product Name	[1-(2-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol
CAS No.	886366-27-4
Molecular Formula	C11H11F3O
Molecular Weight	216.20 g/mol
Synonyms	(1-(2-(Trifluoromethyl)phenyl)cyclopropyl)methanol; α-(2-Trifluoromethylphenyl)cyclopropanemethanol; 1-[2-(Trifluoromethyl)phenyl]cyclopropanemethanol; (1-(2-Trifluoromethylphenyl)cyclopropyl)methanol; 886366-27-4; (1-(o-Trifluoromethylphenyl)cyclopropyl)methanol
EINECS	Contact for details

Quality Control

Our [1-(2-Trifluoromethyl-Phenyl)-Cyclopropyl]-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.