Description

4-(4-Fluorophenyl)-1-Piperidineacetyl Chloride is a high-purity, reactive chemical intermediate featuring a piperidine scaffold and an acid chloride functional group. This compound is critical for the synthesis of complex molecules, particularly in pharmaceutical research and development, where it serves as a key building block. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to introduce specific structural motifs into target compounds.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides that require the 4-fluorophenyl-piperidine moiety.
• Chemical Research & Development: Serves as a versatile precursor for creating novel chemical libraries for high-throughput screening in drug discovery programs.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organocatalysts for asymmetric synthesis.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials and functional polymers.

Basic Information

Product Name	4-(4-Fluorophenyl)-1-Piperidineacetyl Chloride
CAS No.	885955-57-7
Molecular Formula	C13H15ClFNO
Molecular Weight	255.72 g/mol
Synonyms	1-(2-Chloro-2-oxoethyl)-4-(4-fluorophenyl)piperidine; 4-(4-Fluorophenyl)-1-piperidineacetic acid chloride; 2-Chloro-1-[4-(4-fluorophenyl)-1-piperidinyl]ethanone; 4-(p-Fluorophenyl)-1-piperidineacetyl chloride; 4-(4-Fluorophenyl)piperidine-1-acetyl chloride; 1-Piperidineacetyl chloride, 4-(4-fluorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Fluorophenyl)-1-Piperidineacetyl Chloride is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure consistency and purity. Our standard quality commitment includes comprehensive analysis via HPLC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.