Description

(5-Bromo-2-Fluorophenyl)(Phenyl)Methanol is a high-value fluorinated and brominated aromatic alcohol, serving as a critical chiral building block and synthetic intermediate. Its unique bifunctional halogenated structure makes it indispensable for constructing complex molecular architectures with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in medicinal chemistry, ligand synthesis, and specialty polymer development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of halogenated aromatic systems.
• Ligand & Catalyst Development: Used to create chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Monomer or modifier in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a core structure for developing fluorescent tags and molecular probes for diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for scale-up and production of client-specific target molecules.

Basic Information

Product Name	(5-Bromo-2-Fluorophenyl)(Phenyl)Methanol
CAS No.	885124-18-5
Molecular Formula	C13H10BrFO
Molecular Weight	281.12 g/mol
Synonyms	α-(5-Bromo-2-fluorophenyl)benzenemethanol; (5-Bromo-2-fluorophenyl)(phenyl)carbinol; Benzhydrol, 5'-bromo-2'-fluoro-; 1-(5-Bromo-2-fluorophenyl)-1-phenylmethanol; 5-Bromo-2-fluoro-α-phenylbenzenemethanol; [5-Bromo-2-fluorophenyl](phenyl)methanol
EINECS	Contact for details

Quality Control

Every batch of (5-Bromo-2-Fluorophenyl)(Phenyl)Methanol is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the precise requirements for research and scale-up. Our standard quality commitment includes HPLC purity ≥97% (with higher grades available), identity confirmation via spectroscopic methods, and strict control of residual solvents and related substances. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support customer audits and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.