Description

Arry-520 (R Enantiomer) is a high-purity, single-enantiomer small molecule compound of significant interest in advanced pharmaceutical research and development. This compound matters as a critical chiral intermediate or active pharmaceutical ingredient (API) for targeted therapies, where stereochemical purity is paramount for efficacy and safety. It is primarily needed by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the discovery and synthesis of novel therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of complex drug candidates.
• Active Pharmaceutical Ingredient (API) Development: Used in preclinical and clinical research for the formulation of enantiomerically pure active substances.
• Kinase Inhibitor Research: Applied in biochemical and cellular assays to study specific kinase pathways and their role in disease mechanisms.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in analytical laboratories.
• Medicinal Chemistry: Utilized for structure-activity relationship (SAR) studies to optimize drug-like properties and potency.
• Process Chemistry & Scale-Up: Acts as a model compound for developing and optimizing robust, scalable synthetic routes under GMP conditions.

Basic Information

Product Name	Arry-520 (R Enantiomer)
CAS No.	885060-08-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	ARRY-520; ARRY 520 (R enantiomer); (R)-ARRY-520; (R)-Enantiomer of ARRY-520; 4-[(2R)-2-Pyrrolidinyl]methoxy-N-[4-(trifluoromethyl)phenyl]benzamide; KSP Inhibitor ARRY-520 (R form); Filanesib (R enantiomer)
EINECS	Contact for details

Quality Control

Our Arry-520 (R Enantiomer) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets stringent specifications for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee identity, purity, and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% (R enantiomer)
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.