Description

(3-Fluoro-5-Nitrophenyl)Methanol is a versatile fluorinated aromatic building block characterized by its nitro and hydroxymethyl functional groups. This compound is highly valued in advanced organic synthesis for its role as a key intermediate in the development of complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a fluorinated aromatic core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides where the nitro and fluorine groups modulate biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group and potential for functionalization.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing specialized fluorinated dyes and pigments with unique color and stability properties.
• Cross-Coupling Reactions: The functional groups make it a suitable substrate for various palladium-catalyzed cross-coupling reactions, such as Suzuki and Buchwald-Hartwig aminations.

Basic Information

Product Name	(3-Fluoro-5-Nitrophenyl)Methanol
CAS No.	883987-74-4
Molecular Formula	C7H6FNO3
Molecular Weight	171.13 g/mol
Synonyms	3-Fluoro-5-nitrobenzenemethanol; (3-Fluoro-5-nitrophenyl)carbinol; 1-(3-Fluoro-5-nitrophenyl)methanol; Benzenemethanol, 3-fluoro-5-nitro-; 3-Fluoro-5-nitrobenzyl alcohol; 5-Nitro-3-fluorobenzyl alcohol; α-Hydroxymethyl-3-fluoro-5-nitrobenzene
EINECS	Contact for details

Quality Control

Our (3-Fluoro-5-Nitrophenyl)Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.