Description

2-(3-Chlorophenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its value lies in its role as a versatile building block for constructing complex heterocyclic compounds, particularly in the pharmaceutical and agrochemical sectors. This product is primarily needed by R&D chemists and process development scientists in fine chemical, pharmaceutical, and agrochemical manufacturing for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and pesticides with specific activity profiles.
• Material Science Research: Used in the creation of organic ligands for metal-organic frameworks (MOFs) and functional polymers.
• Dye & Pigment Intermediate: Serves as a core structure for synthesizing specialized quinoline-derived colorants and fluorescent markers.
• Academic & Contract Research: Critical reagent for medicinal chemistry programs and exploratory synthetic chemistry in academic and CRO laboratories.
• Custom Synthesis: Foundation for the contract manufacturing of proprietary compounds and bespoke chemical entities for client-specific projects.

Basic Information

Product Name	2-(3-Chlorophenyl)Quinoline-4-Carbonyl Chloride
CAS No.	883526-41-8
Molecular Formula	C₁₆H₉Cl₂NO
Molecular Weight	302.15 g/mol
Synonyms	2-(3-Chlorophenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(3-chlorophenyl)-; 2-(3-Chlorophenyl)quinoline-4-carboxylic acid chloride; 3-Chloro-2-phenylquinoline-4-carbonyl chloride (isomer reference); Quinoline-4-carbonyl chloride, 2-(3-chlorophenyl)- derivative
EINECS	Contact for details

Quality Control

Our production of 2-(3-Chlorophenyl)Quinoline-4-Carbonyl Chloride adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for critical synthesis. Each lot is fully characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment, supporting cGMP-compliant development and manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.