Description

2-(3-Bromophenyl)Quinoline-4-Carbonyl Chloride is a high-purity, reactive organic intermediate of significant importance in advanced chemical synthesis. This compound serves as a critical building block for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel quinoline-based derivatives.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting neurological disorders and cancers.
• Agrochemical Research: Used to develop new quinoline-based fungicides, herbicides, and plant growth regulators.
• Material Science: Building block for creating organic light-emitting diodes (OLEDs), liquid crystals, and other functional electronic materials.
• Chemical Synthesis: Versatile reagent for introducing the 2-(3-bromophenyl)quinoline moiety into more complex molecules via its reactive carbonyl chloride group.
• Academic & Contract Research: Essential for medicinal chemistry programs and structure-activity relationship (SAR) studies in university and CRO laboratories.

Basic Information

Product Name	2-(3-Bromophenyl)Quinoline-4-Carbonyl Chloride
CAS No.	883526-03-2
Molecular Formula	C₁₆H₉BrClNO
Molecular Weight	346.61 g/mol
Synonyms	2-(3-Bromophenyl)-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(3-bromophenyl)-; 3-Bromo-2-phenylquinoline-4-carbonyl chloride; Quinoline-4-carbonyl chloride, 2-(3-bromophenyl)-; 883526-03-2; 2-(3-Bromophenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(3-Bromophenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.