Description

2-(2,4,5-Trifluorophenyl)-Ethanol is a high-value fluorinated aromatic alcohol building block, essential for the synthesis of complex active pharmaceutical ingredients (APIs) and advanced agrochemicals. Its trifluoromethylphenyl ethanol structure provides unique electronic and steric properties that are critical for modulating the bioavailability and metabolic stability of target molecules. This intermediate is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel compounds with enhanced efficacy.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the fluorinated phenyl group enhances biological activity and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Organic Electronic Materials: Employed in the research and production of organic light-emitting diodes (OLEDs) and semiconductors.
• Advanced Polymer Modification: Acts as a monomer or modifier to introduce fluorine into polymer chains, enhancing chemical resistance and surface properties.
• Chemical Research & Development: A versatile building block in medicinal chemistry and material science for structure-activity relationship (SAR) studies and novel compound library synthesis.

Basic Information

Product Name	2-(2,4,5-Trifluorophenyl)-Ethanol
CAS No.	883267-70-7
Molecular Formula	C8H7F3O
Molecular Weight	176.14 g/mol
Synonyms	2-(2,4,5-Trifluorophenyl)ethan-1-ol; 2,4,5-Trifluorophenethyl Alcohol; (2,4,5-Trifluorophenyl)ethanol; 2-(2,4,5-Trifluorophenyl)ethyl Alcohol; α-(2,4,5-Trifluorophenyl)ethanol; 883267-70-7; 2-(2,4,5-Trifluorophenyl)ethanol
EINECS	Contact for details

Quality Control

Every batch of 2-(2,4,5-Trifluorophenyl)-Ethanol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical and agrochemical synthesis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.