Description

Azido-Peg2-Ch2Co2H is a heterobifunctional polyethylene glycol (PEG) linker featuring a reactive azide group and a carboxylic acid terminus. This compound is essential for creating stable, biocompatible conjugates in bioconjugation and materials science, enabling click chemistry via its azide functionality. It is primarily used by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing drug delivery systems, diagnostic probes, and functionalized surfaces.

Application

• Bioconjugation reagent for attaching biomolecules (e.g., peptides, antibodies, oligonucleotides) to surfaces or other molecules via copper-free or copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Key building block in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutic agents.
• Surface functionalization of nanoparticles, quantum dots, and polymers to impart water solubility and bioactivity.
• Preparation of cross-linked hydrogels and biomaterials for tissue engineering and 3D cell culture applications.
• Modification of solid supports and resins for affinity chromatography and biosensor development.
• Introduction of PEG spacers into small molecule drug candidates to improve pharmacokinetic properties.
• Tool compound for chemical biology research, including protein labeling and activity-based profiling.

Basic Information

Product Name	Azido-Peg2-Ch2Co2H
CAS No.	882518-90-3
Molecular Formula	C9H17N3O5
Molecular Weight	247.25 g/mol
Synonyms	2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]acetic acid; Azido-PEG2-acetic acid; 3,6,9-Trioxa-12-azadodecan-12-oic acid, 12-azido-; Azido-PEG2-CH2COOH; N3-PEG2-acid; Azido-EG2-CH2CO2H; Azido(triethylene glycol)acetic acid; PEG2-azide-acid
EINECS	Contact for details

Quality Control

Our Azido-Peg2-Ch2Co2H is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FT-IR, to ensure high purity and consistent performance for sensitive research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or oil
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.