Description

2(1H)-Isoquinolinecarboxylic Acid, 1-[(4-Azido-3-Iodophenyl)Methyl]-6,7-Bis[(Ethoxycarbonyl)Oxy]-3,4-Dihydro-, 9H-Fluoren-9-Ylmethyl Ester is a sophisticated, multi-functional organic compound designed for advanced chemical synthesis. This molecule is engineered as a key building block and photoaffinity labeling reagent, offering precise reactivity for probing biological systems and constructing complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and agrochemical sectors for developing novel active ingredients and diagnostic tools.

Application

• Photoaffinity Labeling Probes: A critical reagent for cross-linking studies in biochemistry and molecular biology to investigate protein-ligand interactions and identify binding sites.
• Pharmaceutical Intermediate: Serves as a versatile synthon in the multi-step synthesis of potential drug candidates, particularly in oncology and CNS research.
• Bioconjugation Chemistry: Used for the site-specific modification of biomolecules (peptides, proteins, oligonucleotides) due to its reactive azido and ester functional groups.
• Material Science Research: Employed in the development of advanced polymers and smart materials that respond to light stimuli.
• Agrochemical Development: Acts as a high-value intermediate in the synthesis of novel, targeted crop protection agents.
• Chemical Biology Tool Development: Integral for creating activity-based probes (ABPs) to profile enzyme function and activity in complex biological samples.

Basic Information

Product Name	2(1H)-Isoquinolinecarboxylic Acid, 1-[(4-Azido-3-Iodophenyl)Methyl]-6,7-Bis[(Ethoxycarbonyl)Oxy]-3,4-Dihydro-, 9H-Fluoren-9-Ylmethyl Ester
CAS No.	880475-04-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1-[(4-Azido-3-iodophenyl)methyl]-6,7-bis(ethoxycarbonyloxy)-3,4-dihydro-2(1H)-isoquinolinecarboxylic acid 9H-fluoren-9-ylmethyl ester; Fmoc-protected azido-iodo isoquinoline derivative; Photoaffinity labeling reagent CAS 880475-04-7; 9-Fluorenylmethyl 1-[(4-azido-3-iodobenzyl)]-6,7-bis(ethoxycarbonyloxy)-3,4-dihydroisoquinoline-2(1H)-carboxylate; Azido-Iodo-Fmoc Isoquinoline Ester
EINECS	Contact for details

Quality Control

Every batch of this high-purity biochemical reagent is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to verify identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment to ensure traceability and support your research and development documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent degradation from oxidation and moisture. Allow the container to reach room temperature in a desiccator before opening to minimize condensation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.