Description

Benzenemethanol, 2,6-Difluoro-A-(Trifluoromethyl)- is a high-value, multi-fluorinated benzyl alcohol derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring both difluoro and trifluoromethyl substituents, provides exceptional utility for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where fluorine incorporation enhances efficacy and environmental profile.
• Material Science Research: Serves as a precursor for specialty monomers and polymers, contributing to materials with unique surface properties and chemical resistance.
• Liquid Crystal & OLED Materials: A potential intermediate for creating fluorinated components in electronic display and lighting technologies.
• Organic Synthesis & Catalysis: Valuable reagent for introducing complex fluorinated aromatic groups in cross-coupling reactions and ligand design.

Basic Information

Product Name	Benzenemethanol, 2,6-Difluoro-A-(Trifluoromethyl)-
CAS No.	878204-73-0
Molecular Formula	C9H5F5O
Molecular Weight	224.13 g/mol
Synonyms	2,6-Difluoro-α-(trifluoromethyl)benzyl alcohol; α-(Trifluoromethyl)-2,6-difluorobenzyl alcohol; (2,6-Difluorophenyl)(trifluoromethyl)methanol; 2,6-Difluoro-α-(trifluoromethyl)benzenemethanol; 878204-73-0; (2,6-Difluorophenyl)(trifluoromethyl)carbinol
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for this advanced intermediate. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and MS, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support custom synthesis to meet specific purity or impurity profile requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.