Description

1-Methyl-5-Thien-2-Yl-1H-Pyrazole-3-Carbonyl Chloride is a high-value, reactive chemical intermediate essential for advanced organic synthesis. This compound serves as a critical building block for constructing complex heterocyclic molecules, enabling the development of novel active ingredients. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new drug candidates and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and metabolic disorders.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic core structure.
• Material Science Research: Employed in the creation of specialized polymers and organic electronic materials due to its functionalized pyrazole-thiophene scaffold.
• Chemical Biology & Proteomics: Acts as a versatile reagent for labeling and modifying biomolecules in probe development and bioconjugation strategies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries for high-throughput screening.

Basic Information

Product Name	1-Methyl-5-Thien-2-Yl-1H-Pyrazole-3-Carbonyl Chloride
CAS No.	876316-46-0
Molecular Formula	C9H7ClN2OS
Molecular Weight	226.68 g/mol
Synonyms	1-Methyl-5-(thiophen-2-yl)-1H-pyrazole-3-carbonyl chloride; 5-(Thiophen-2-yl)-1-methyl-1H-pyrazole-3-carbonyl chloride; 1-Methyl-5-(2-thienyl)-1H-pyrazole-3-carbonyl chloride; 1-Methyl-5-thien-2-yl-1H-pyrazole-3-carbonyl chloride; 1-Methyl-5-(thiophen-2-yl)-1H-pyrazole-3-carboxylic acid chloride; Pyrazole-3-carbonyl chloride, 1-methyl-5-(2-thienyl)-; 876316-46-0
EINECS	Contact for details

Quality Control

Our 1-Methyl-5-Thien-2-Yl-1H-Pyrazole-3-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP (Current Good Manufacturing Practice) environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as an acid chloride, it should be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from moisture, strong bases, and oxidizing agents. Handle and store only in compatible, dry glass or fluorinated polymer containers.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.