Description

(2-Iodo-4-(Trifluoromethyl)Phenyl)Methanol is a versatile and high-value organoiodine building block characterized by its trifluoromethyl and hydroxymethyl functional groups. This compound is essential for advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals where its unique halogenated aromatic structure enables precise molecular modifications. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of fluorine-containing drug candidates targeting CNS disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, facilitating challenging cross-coupling and fluorination reactions.
• Material Science Research: Employed in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and steric properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for imaging and diagnostic applications, leveraging the iodine atom for further functionalization.

Basic Information

Product Name	(2-Iodo-4-(Trifluoromethyl)Phenyl)Methanol
CAS No.	873005-49-3
Molecular Formula	C8H6F3IO
Molecular Weight	302.04 g/mol
Synonyms	2-Iodo-α-(trifluoromethyl)benzyl alcohol; [2-Iodo-4-(trifluoromethyl)phenyl]methanol; 1-(2-Iodo-4-(trifluoromethyl)phenyl)methanol; (2-Iodo-4-trifluoromethylphenyl)methanol; α-(Trifluoromethyl)-2-iodobenzyl alcohol; 2-Iodo-4-(trifluoromethyl)benzenemethanol; Benzenemethanol, 2-iodo-α-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our (2-Iodo-4-(Trifluoromethyl)Phenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, assay, and impurity profiles. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.