Description

(3-Fluoro-5-Trifluoromethylphenyl)-p-Tolyl-Methanone is a high-purity fluorinated aromatic ketone building block of significant interest in advanced organic synthesis. Its value lies in its unique trifluoromethyl and fluorine substituents, which are critical for modulating the electronic properties, metabolic stability, and lipophilicity of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new drug candidates, particularly for incorporating fluorine motifs to enhance bioavailability and binding affinity.
• Agrochemical Synthesis: Used in the design and synthesis of advanced pesticides and herbicides, where the fluorine atoms contribute to improved environmental stability and efficacy.
• Material Science Research: Acts as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its rigid, fluorinated aromatic structure.
• Chemical Biology Probes: Employed in the development of molecular probes and tags for studying biological systems, leveraging its distinct spectroscopic signature.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	(3-Fluoro-5-Trifluoromethylphenyl)-p-Tolyl-Methanone
CAS No.	872088-12-5
Molecular Formula	C15H10F4O
Molecular Weight	282.24 g/mol
Synonyms	1-(3-Fluoro-5-(trifluoromethyl)phenyl)-1-(4-methylphenyl)methanone; 3'-Fluoro-5'-(trifluoromethyl)-4-methylbenzophenone; p-Tolyl 3-fluoro-5-(trifluoromethyl)phenyl ketone; (3-Fluoro-5-trifluoromethylphenyl)(4-methylphenyl)methanone; 4-Methyl-3',5'-bis(trifluoromethyl)benzophenone (common misnomer check); Benzophenone, 3'-fluoro-5'-(trifluoromethyl)-4-methyl-
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our standard material typically meets a purity specification of ≥97% (by HPLC), with stringent control over related substances. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.