Description

2-Amino-2-(3,4,5-trifluorophenyl)ethan-1-ol is a high-value fluorinated amino alcohol building block, essential for the synthesis of complex active pharmaceutical ingredients (APIs). Its unique trifluoromethylphenyl motif is critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing new drug candidates, particularly in therapeutic areas requiring precise molecular engineering.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, especially for central nervous system (CNS) and anti-infective drugs.
• Agrochemical Research: Used in the development of advanced fluorinated pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Potential building block for specialty polymers and advanced materials requiring fluorinated aromatic components.
• Chemical Biology Probes: Utilized in the design of molecular probes for studying enzyme mechanisms and protein interactions.

Basic Information

Product Name	2-Amino-2-(3,4,5-trifluorophenyl)ethan-1-ol
CAS No.	870852-79-2
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-Amino-2-(3,4,5-trifluorophenyl)ethanol; 1-(3,4,5-Trifluorophenyl)-2-aminoethanol; 2-Amino-1-(3,4,5-trifluorophenyl)ethanol; (3,4,5-Trifluorophenyl)glycinol; α-Amino-3,4,5-trifluorobenzeneethanol; 870852-79-2; 2-(3,4,5-Trifluorophenyl)-2-aminoethanol
EINECS	Contact for details

Quality Control

Our 2-Amino-2-(3,4,5-trifluorophenyl)ethan-1-ol is manufactured under strict quality management systems. We provide material with standard purity grades suitable for research and commercial synthesis. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles. Our quality commitment ensures reliable consistency and traceability for your critical development and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle the material under a dry inert atmosphere for long-term storage or after opening the original container. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.