Description

4-Methyl-3-[[3-[2-(Methylamino)-4-Pyrimidinyl]-2-Pyridinyl]Oxy]-n-[3-(Trifluoromethyl)Phenyl]Benzamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant commercial interest for its role in the research and development of targeted therapeutic agents, particularly in oncology. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational kinase inhibitors for cancer therapy.
• Biochemical Research: Used as a reference standard or probe compound in enzymatic assays and target validation studies.
• Preclinical Development: Serves as a critical material for formulation studies, pharmacokinetic profiling, and toxicology assessments of new chemical entities.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Employed in university and institutional labs for medicinal chemistry programs focused on heterocyclic compounds.

Basic Information

Product Name	4-Methyl-3-[[3-[2-(Methylamino)-4-Pyrimidinyl]-2-Pyridinyl]Oxy]-n-[3-(Trifluoromethyl)Phenyl]Benzamide
CAS No.	870223-96-4
Molecular Formula	C25H20F3N5O2
Molecular Weight	479.45 g/mol
Synonyms	N-[3-(Trifluoromethyl)phenyl]-4-methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)benzamide; 870223-96-4; Benzamide, N-[3-(trifluoromethyl)phenyl]-4-methyl-3-[[3-[2-(methylamino)-4-pyrimidinyl]-2-pyridinyl]oxy]-; 4-Methyl-3-({3-[2-(methylamino)pyrimidin-4-yl]pyridin-2-yl}oxy)-N-[3-(trifluoromethyl)phenyl]benzamide
EINECS	Contact for details

Quality Control

Our 4-Methyl-3-[[3-[2-(Methylamino)-4-Pyrimidinyl]-2-Pyridinyl]Oxy]-n-[3-(Trifluoromethyl)Phenyl]Benzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.