Description

2-[4-[[(4S,5R)-4,5-Bis(4-Chlorophenyl)-2-[4-(1,1-Dimethylethyl)-2-Ethoxyphenyl]-4,5-Dihydro-1H-Imidazol-1-Yl]Carbonyl]-1-Piperazinyl]-1-(4-Morpholinyl)Ethanone is a sophisticated, high-purity organic compound featuring a complex molecular architecture with multiple functional groups. This compound is of significant value as a key advanced pharmaceutical intermediate or a research-grade chemical building block for the synthesis of novel active molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, particularly in areas requiring chiral specificity and complex heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or other specialized therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with imidazoline and morpholine pharmacophores.
• Chemical Biology Probe Development: Acts as a precursor for creating specialized probes to study biological pathways and protein interactions due to its complex, modifiable structure.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for new active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services for the global pharmaceutical industry.

Basic Information

Item	Details
Product Name	2-[4-[[(4S,5R)-4,5-Bis(4-Chlorophenyl)-2-[4-(1,1-Dimethylethyl)-2-Ethoxyphenyl]-4,5-Dihydro-1H-Imidazol-1-Yl]Carbonyl]-1-Piperazinyl]-1-(4-Morpholinyl)Ethanone
CAS No.	870120-40-4
Molecular Formula	C44H48Cl2N4O4
Molecular Weight	767.78 g/mol
Synonyms	1-(4-Morpholinyl)-2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(tert-butyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]ethanone; (4S,5R)-1-[4-(2-Morpholin-4-yl-2-oxoethyl)piperazine-1-carbonyl]-4,5-bis(4-chlorophenyl)-2-[4-(tert-butyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazole; 870120-40-4; UNII-7K3K8J7J4F; Ethanone, 1-(4-morpholinyl)-2-[4-[[(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-(1,1-dimethylethyl)-2-ethoxyphenyl]-4,5-dihydro-1H-imidazol-1-yl]carbonyl]-1-piperazinyl]-
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch is characterized and tested using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and chiral integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support development and commercial projects with cGMP-compliant manufacturing options and full regulatory documentation support.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.