Description

Platencin is a potent, naturally occurring antibiotic belonging to the novel platensimycin class of compounds. It represents a significant advancement in antibiotic research due to its unique mechanism of action, targeting bacterial fatty acid synthesis. This product is essential for pharmaceutical R&D, particularly for researchers developing new antibacterial agents to combat drug-resistant pathogens. Platencin CAS NO 869898-86-2 serves as a critical reference standard and a promising lead compound in antimicrobial discovery programs.

Application

• Pharmaceutical Reference Standard: Used for the identification, purity assessment, and quantification of Platencin in analytical method development and validation (HPLC, LC-MS).
• Antibacterial Research & Development: Serves as a key lead compound and biological tool for studying novel mechanisms of action against Gram-positive bacteria, including MRSA and VRE.
• Biochemical Assays: Employed in in vitro enzymatic assays to study the inhibition of bacterial FabF and FabH enzymes in the fatty acid biosynthesis pathway.
• Microbiology Studies: Used to determine minimum inhibitory concentrations (MICs) and to investigate bacterial resistance mechanisms.
• Structure-Activity Relationship (SAR) Studies: Provides the core scaffold for medicinal chemistry programs aimed at optimizing potency, pharmacokinetics, and spectrum of activity.
• Academic Research: Utilized in university and institutional labs for fundamental research on antibiotic discovery and bacterial physiology.

Basic Information

Product Name	Platencin
CAS No.	869898-86-2
Molecular Formula	C24H33NO5
Molecular Weight	415.52 g/mol
Synonyms	BAY 73-7388; (3S,4R)-3-[(1R,2S,5S,6R)-5,6-Dihydroxy-7-oxabicyclo[4.1.0]hept-2-yl]-4-hydroxy-8-methyl-2-oxo-1,2,3,4-tetrahydroquinoline-3-carboxylic acid; Platencin antibiotic; Platensinycin analog; Antibiotic from Streptomyces platensis.
EINECS	Contact for details

Quality Control

Our Platencin is produced under strict quality management to ensure high purity and batch-to-batch consistency suitable for research applications. Identity and purity are confirmed through a suite of analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, related substances, and analytical data is provided with each batch to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and potency. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.