Description

2'-Amino-2'-Deoxy-5-Methylcytidine is a modified nucleoside analog of significant interest in advanced pharmaceutical and biochemical research. This compound serves as a critical building block and intermediate in the synthesis of oligonucleotides and other nucleoside-based therapeutics. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel antiviral agents, anticancer drugs, and molecular biology tools. The high-purity material is essential for ensuring the efficacy and reproducibility of experimental and developmental work.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel nucleoside-based antiviral and anticancer therapeutics.
• Oligonucleotide Synthesis: Used as a modified building block for constructing DNA/RNA analogs with altered properties for research and therapeutic applications.
• Biochemical Research: Employed in enzymatic studies, metabolic pathway analysis, and as a substrate or inhibitor for nucleoside/nucleotide-processing enzymes.
• Antisense Technology: A component in the synthesis of antisense oligonucleotides designed for gene silencing and targeted therapy.
• Prodrug Development: Investigated as a precursor molecule in the design of prodrugs to enhance drug delivery and bioavailability.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	2'-Amino-2'-Deoxy-5-Methylcytidine
CAS No.	869729-45-3
Molecular Formula	C10H16N4O4
Molecular Weight	256.26 g/mol
Synonyms	5-Methyl-2'-deoxy-2'-aminocytidine; 2'-Amino-2'-deoxy-5-methylcytidine; 2'-Amino-5-methyl-2'-deoxycytidine; 5-Methyl-2'-amino-2'-deoxycytidine; 2'-Deoxy-2'-amino-5-methylcytidine; 2'-NH2-5-Me-dC; dC(2'NH2,5Me)
EINECS	Contact for details

Quality Control

Our 2'-Amino-2'-Deoxy-5-Methylcytidine is manufactured under stringent quality systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.