Description

Mpeg8-N3 CAS NO 869718-80-9 is a heterobifunctional polyethylene glycol (PEG) derivative featuring an azide (N3) group at one terminus and a methoxy group at the other. This compound is a critical building block in bioconjugation and materials science, enabling the creation of stable, site-specific linkages via click chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for applications such as drug delivery system development, surface functionalization, and polymer modification.

Application

• Bioconjugation and Linker Chemistry: Acts as a hydrophilic spacer to conjugate biomolecules (e.g., peptides, antibodies, oligonucleotides) to other entities via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC).
• Drug Delivery System Development: Used to functionalize liposomes, nanoparticles, and micelles to enhance solubility, prolong circulation time, and enable targeted delivery of therapeutic agents.
• Surface Modification and Functionalization: Employed to create bio-inert or bioactive coatings on medical devices, biosensors, and diagnostic platforms to reduce non-specific binding or introduce specific functionalities.
• Polymer and Materials Science: Serves as a macromonomer or cross-linker for synthesizing hydrogels, smart polymers, and functional materials with tailored properties.
• Diagnostic Reagent Preparation: Utilized in the development of fluorescent probes, imaging agents, and assay components where a stable, water-soluble linker is required.
• Protein PEGylation: Facilitates the site-specific modification of proteins to improve pharmacokinetic profiles, stability, and reduce immunogenicity.

Basic Information

Product Name	Mpeg8-N3
CAS No.	869718-80-9
Molecular Formula	C21H41N3O9
Molecular Weight	479.57 g/mol
Synonyms	mPEG8-Azide; 8-Azido-3,6,9,12,15,18,21-heptaoxatricosan-1-ol; Methoxy-PEG8-azide; α-Methoxy-ω-azido-octa(ethylene glycol); Azido-PEG8-OMe; O-(2-Azidoethyl)-O'-methyl-nonaethylene glycol; mPEG8-N3; Azido-PEG8-methyl ether
EINECS	Contact for details

Quality Control

Our Mpeg8-N3 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive research and development applications. Certificates of Analysis (COA) detailing purity, identity, and functional group integrity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Molecular Weight Confirmation (MS)	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.