Description

N4-(Diisobutylaminomethylidene)-5-Iodo-2'-o-Methyl-Cytidine is a sophisticated, modified nucleoside derivative designed for advanced research and development applications. This compound is critical for its role as a key intermediate or building block in the synthesis of novel oligonucleotides and therapeutic agents. It is primarily sought after by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on nucleic acid chemistry, antiviral drug discovery, and the development of targeted molecular probes.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Oligonucleotide Synthesis: Used in the research and development of modified oligonucleotides for antisense, siRNA, and aptamer technologies.
• Biochemical Research: Serves as a specialized substrate or probe in enzymatic studies and nucleic acid metabolism research.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the pharmacokinetic properties of nucleoside analogs.
• Diagnostic Probe Development: Utilized in creating labeled nucleotides for molecular diagnostics and imaging applications.

Basic Information

Product Name	N4-(Diisobutylaminomethylidene)-5-Iodo-2'-o-Methyl-Cytidine
CAS No.	869355-40-8
Molecular Formula	C19H31IN4O5
Molecular Weight	546.38 g/mol
Synonyms	5-Iodo-2'-O-methyl-N4-(diisobutylaminomethylene)cytidine; 2'-O-Methyl-5-iodocytidine N4-(diisobutylaminomethylene) derivative; 5-I-2'-OMe-Cytidine amidine derivative; N4-(Diisobutylaminomethylene)-5-iodo-2'-O-methylcytidine; 869355-40-8; Modified Cytidine Derivative; Amidite Precursor; Nucleoside Amidine
EINECS	Contact for details

Quality Control

Every batch of N4-(Diisobutylaminomethylidene)-5-Iodo-2'-o-Methyl-Cytidine is manufactured under strict quality management systems and undergoes rigorous analytical testing. We ensure compliance with high-purity standards suitable for research and pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.