Description

5''-Oxo-2''-Deoxy-8,5''-Cycloadenosine is a chemically modified nucleoside analog, representing a specialized building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in antiviral and anticancer research where modified nucleosides are critical. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleotide-based therapeutics and diagnostic probes.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel nucleoside analog drugs targeting viral polymerases.
• Antiviral Research: Used in medicinal chemistry programs to develop potential therapeutics against DNA and RNA viruses.
• Oncology Drug Discovery: Acts as a scaffold for creating modified nucleotides that may interfere with cancer cell DNA replication.
• Biochemical Probe Development: Utilized in the design of labeled or modified nucleotides for studying enzyme mechanisms and nucleic acid interactions.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing high-value, complex organic molecules.
• Academic Research: A valuable tool for universities and research institutes studying nucleic acid chemistry, cyclonucleoside formation, and structure-activity relationships.

Basic Information

Product Name	5''-Oxo-2''-Deoxy-8,5''-Cycloadenosine
CAS No.	869355-08-8
Molecular Formula	C11H13N5O4
Molecular Weight	279.26 g/mol
Synonyms	8,5'-Cyclo-2'-deoxy-5'-oxoadenosine; 2'-Deoxy-8,5'-cycloadenosine-5'-one; 5'-Oxo-2'-deoxy-8,5'-cycloadenosine; 8,5'-c-2'-dA-5'-one; 8,5'-Cycloadenosine-5'-one, 2'-deoxy-; Adenosine, 2'-deoxy-8,5'-cyclo-, 5'-oxo-; 869355-08-8; 5'-Oxo-8,5'-cyclo-2'-deoxyadenosine
EINECS	Contact for details

Quality Control

Our 5''-Oxo-2''-Deoxy-8,5''-Cycloadenosine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.