Description

2-((Dimethylaminomethylidene)Amino)Purine-2'-Deoxy-Riboside CAS NO 869355-02-2 is a high-purity nucleoside analog derivative, serving as a critical building block in advanced pharmaceutical and biochemical research. This compound is valued for its role in the synthesis of modified oligonucleotides and as a key intermediate in developing novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on antiviral drug development, genetic research, and nucleotide chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside-based antiviral and anticancer agents.
• Oligonucleotide Synthesis: Building block for creating modified DNA/RNA strands for research, diagnostics, and therapeutic applications (e.g., antisense oligonucleotides).
• Biochemical Research: Used in enzymatic studies, polymerase investigations, and as a substrate analog to study nucleic acid metabolism and repair mechanisms.
• Pro-drug Development: Intermediate for designing membrane-permeable pro-drugs of active nucleotide analogs.
• Labeling and Tracing: Potential starting material for synthesizing radiolabeled or fluorescently tagged nucleotides for tracking and imaging studies.

Basic Information

Product Name	2-((Dimethylaminomethylidene)Amino)Purine-2'-Deoxy-Riboside
CAS No.	869355-02-2
Molecular Formula	C13H19N7O4
Molecular Weight	337.34 g/mol
Synonyms	2-((Dimethylaminomethylene)amino)purine-2'-deoxyriboside; 2'-Deoxy-2-((dimethylaminomethylene)amino)purine riboside; N2-((Dimethylamino)methylene)-2'-deoxyguanosine analog; 2-Amino-6-((dimethylaminomethylene)amino)purine-2'-deoxyriboside; dG(DMF) analog; Modified Deoxyguanosine Derivative; CAS 869355-02-2
EINECS	Contact for details

Quality Control

Every batch of 2-((Dimethylaminomethylidene)Amino)Purine-2'-Deoxy-Riboside is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles is provided with each shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere or with desiccant after each use to prevent degradation. For long-term storage, consider storing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.