Description

2-(Dimethylaminomethylidene)Amino-6-Methoxylamino-9-(β-D-2-Deoxyribofuranosyl)Purine is a sophisticated nucleoside analog building block of significant interest in advanced pharmaceutical research and development. This compound matters as a key synthetic intermediate for the creation of novel antiviral and anticancer agents, enabling the exploration of new therapeutic mechanisms. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleoside chemistry and prodrug development.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a specialized substrate or inhibitor in enzymatic studies related to DNA/RNA synthesis and repair pathways.
• Prodrug Development: Acts as a key building block for designing prodrugs aimed at improving drug delivery, bioavailability, and targeting specificity.
• Antiviral Agent Synthesis: Employed in the research and development of potential therapeutic agents targeting viral polymerases.
• Oncology Research: Utilized in the discovery of compounds that interfere with nucleotide metabolism in cancer cells.
• Fine Chemical Synthesis: Provides a versatile scaffold for medicinal chemists to create libraries of modified nucleosides for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-(Dimethylaminomethylidene)Amino-6-Methoxylamino-9-(β-D-2-Deoxyribofuranosyl)Purine
CAS No.	869354-99-4
Molecular Formula	C₁₄H₂₁N₇O₄
Molecular Weight	351.36 g/mol
Synonyms	9-[(2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-[(E)-[dimethylamino)methylidene]amino]-6-methoxylaminopurine; 2-[(E)-[(Dimethylamino)methylene]amino]-6-(methoxyamino)-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]purine; 2-((Dimethylaminomethylene)amino)-6-methoxylamino-9-(2-deoxy-β-D-ribofuranosyl)purine; Modified 2'-Deoxyguanosine Analog; Nucleoside Analog Intermediate
EINECS	Contact for details

Quality Control

Our 2-(Dimethylaminomethylidene)Amino-6-Methoxylamino-9-(β-D-2-Deoxyribofuranosyl)Purine is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and development. All materials undergo rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.