Description

3'-Azido-N6-Benzoyl-2',3'-Dideoxyadenosine is a chemically modified nucleoside analog, specifically designed as a key synthetic intermediate. This compound is of significant value in pharmaceutical research and development, particularly for the synthesis of novel antiviral and anticancer agents. It is primarily needed by research institutions, pharmaceutical companies, and CROs (Contract Research Organizations) engaged in nucleoside chemistry and the development of prodrugs or modified nucleic acid therapeutics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of nucleoside reverse transcriptase inhibitors (NRTIs) and other antiviral drug candidates.
• Antiviral Research: Used in the development of prodrugs targeting viruses such as HIV, HBV, and HCV, leveraging its azido and dideoxy modifications.
• Oncology Drug Discovery: Serves as a precursor for creating modified nucleosides with potential anticancer activity.
• Biochemical Probe Synthesis: Utilized in the preparation of labeled or tagged nucleosides for studying enzyme mechanisms and cellular processes.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties.
• Academic Research: Employed in universities and research labs for fundamental studies in organic synthesis and nucleic acid chemistry.

Basic Information

Product Name	3'-Azido-N6-Benzoyl-2',3'-Dideoxyadenosine
CAS No.	869354-89-2
Molecular Formula	C17H15N7O3
Molecular Weight	365.35 g/mol
Synonyms	3'-Azido-N6-benzoyl-2',3'-dideoxyadenosine; 3'-Azido-2',3'-dideoxy-N6-benzoyladenosine; 3'-Azido-N6-Bz-2',3'-ddA; 3'-N3-N6-Bz-2',3'-ddA; 2',3'-Dideoxy-3'-azido-N6-benzoyladenosine; 9-[(2R,5S)-5-(Azidomethyl)tetrahydrofuran-2-yl]-N-benzyl-9H-purin-6-amine (related); AZT-N6-Benzoyl intermediate; Contact for details on additional aliases.
EINECS	Not yet assigned. Contact for details.

Quality Control

Our 3'-Azido-N6-Benzoyl-2',3'-Dideoxyadenosine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider storing desiccated under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.