Description

2-Amino-N2-Isobutyryl-2'-o-Methyladenosine is a chemically modified nucleoside derivative, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its role in the synthesis of oligonucleotides and nucleotide analogs, enabling precise modifications to RNA structure and function. It is essential for researchers and manufacturers in the fields of therapeutic oligonucleotide development, antisense technology, and molecular biology, where high-purity intermediates are critical for successful outcomes.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleotide-based therapeutics, including antisense oligonucleotides and siRNA.
• Biochemical Research: Used as a modified building block in oligonucleotide synthesis to study RNA structure, stability, and biological activity.
• Proteomics & Diagnostics: Can be incorporated into probes and tools for studying nucleic acid-protein interactions and diagnostic assay development.
• Academic & Industrial R&D: Serves as a specialty reagent for exploring new mechanisms in gene expression and regulation.

Basic Information

Product Name	2-Amino-N2-Isobutyryl-2'-o-Methyladenosine
CAS No.	869354-85-8
Molecular Formula	C16H22N6O5
Molecular Weight	378.39 g/mol
Synonyms	2'-O-Methyl-2-amino-N2-isobutyryladenosine; 2'-O-Me-2-N-ibu-rA; 2-Amino-2'-O-methyl-N2-isobutyryladenosine; 2'-O-Methyl-N2-isobutyryl-2-aminoadenosine; 2'-O-Methyl-2-N-isobutyrylguanosine (common class name); N2-Isobutyryl-2'-O-methyl-2-aminoadenosine; 2'-OMe-2-N-ibu-A; Modified Adenosine Derivative
EINECS	Contact for details

Quality Control

Our 2-Amino-N2-Isobutyryl-2'-o-Methyladenosine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.