Description

Benzyl-Peg9-N3 is a heterobifunctional polyethylene glycol (PEG) derivative featuring a benzyl group at one terminus and an azide (N3) group at the other. This molecular architecture is critical for creating stable, biocompatible linkages in advanced bioconjugation and materials science applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing targeted drug delivery systems, modifying biomolecules, and engineering functional hydrogels.

Application

• Bioconjugation and Linker Chemistry: Acts as a versatile spacer and linker for "click chemistry" reactions, specifically copper-catalyzed azide-alkyne cycloaddition (CuAAC), to attach targeting ligands, drugs, or probes to antibodies, proteins, and nanoparticles.
• Drug Delivery System Development: Used to functionalize liposomes, polymeric micelles, and other nanocarriers to enhance solubility, prolong circulation time, and enable site-specific targeting.
• PEGylation Reagent: Serves as a PEGylating agent to modify therapeutic peptides, proteins, and oligonucleotides, improving their pharmacokinetic profiles and reducing immunogenicity.
• Surface Functionalization: Employed to create azide-terminated surfaces on chips, beads, and medical devices for subsequent immobilization of biomolecules via bio-orthogonal chemistry.
• Hydrogel and Biomaterial Synthesis: A key building block in the cross-linking and fabrication of PEG-based hydrogels for 3D cell culture, tissue engineering, and controlled release applications.
• Diagnostic Probe Assembly: Facilitates the construction of complex diagnostic probes and imaging agents by linking reporting modules to recognition elements.

Basic Information

Product Name	Benzyl-Peg9-N3
CAS No.	868594-49-4
Molecular Formula	C31H55N3O10
Molecular Weight	~629.8 g/mol
Synonyms	Benzyl-PEG9-azide; Benzyl-PEG9-N3; Benzyl-triethylene glycol nonaethylene glycol) azide; 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-Azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl benzyl ether; Azido-PEG9-Benzyl; N3-PEG9-O-Benzyl; Benzyloxy-PEG9-azide
EINECS	Contact for details

Quality Control

Our Benzyl-Peg9-N3 is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance for sensitive research and development applications. A comprehensive Certificate of Analysis (COA) is provided, detailing results from NMR, HPLC, and other relevant assays to verify identity, purity, and functional group integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This product is hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Group Integrity	Azide content confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.