Description

(3-Iodo-5-Trifluoromethyl-Phenyl)-Methanol is a high-value, multi-functional aromatic building block featuring both an iodine substituent and a trifluoromethyl group on a benzyl alcohol core. This unique structure makes it a critical intermediate for the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its halogen and fluorine atoms enable precise molecular tuning. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with specific electronic and steric properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry for creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group often contributes to improved activity and environmental profile.
• Ligand & Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis for cross-coupling and other organic transformations.
• Material Science Research: Employed in the creation of functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated structure.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems and mechanisms.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	(3-Iodo-5-Trifluoromethyl-Phenyl)-Methanol
CAS No.	868167-58-2
Molecular Formula	C8H6F3IO
Molecular Weight	302.04 g/mol
Synonyms	[3-Iodo-5-(trifluoromethyl)phenyl]methanol; (3-Iodo-5-trifluoromethylphenyl)methanol; α,α,α-Trifluoro-3-iodo-5-methylbenzyl alcohol; 5-(Hydroxymethyl)-1-iodo-3-(trifluoromethyl)benzene; 3-Iodo-5-(trifluoromethyl)benzenemethanol; 1-Iodo-3-(hydroxymethyl)-5-(trifluoromethyl)benzene; 868167-58-2; Benzenemethanol, 3-iodo-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Every batch of (3-Iodo-5-Trifluoromethyl-Phenyl)-Methanol is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results for identity, assay, and impurity profile. Our quality protocols are designed to support cGMP and ISO compliant workflows for our partners in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.