Description

2-Propenoyl Chloride, 3-(3-Hydroxyphenyl)-, (2E)- is a specialized, high-purity chemical intermediate featuring a conjugated system with both an acid chloride and a phenolic hydroxyl group. This unique bifunctional structure makes it a versatile building block for synthesizing advanced materials and active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries seeking to introduce specific photoreactive or cross-linking functionalities into their target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing specific photochemical properties.
• Agrochemical Synthesis: Used to create advanced active ingredients for crop protection agents, leveraging its reactive sites for structural diversification.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for producing specialty polymers, including photosensitive resins, adhesives, and coatings with tailored properties.
• Liquid Crystal & OLED Materials: Building block for synthesizing advanced organic electronic materials due to its planar, conjugated structure and functional handles.
• Bioconjugation & Probe Development: Employed in research to create fluorescent probes or to attach bioactive molecules to surfaces or carriers via its acid chloride group.
• Academic & Contract Research: Essential reagent for methodological development and exploring new chemical reactions in organic and medicinal chemistry research.

Basic Information

Product Name	2-Propenoyl Chloride, 3-(3-Hydroxyphenyl)-, (2E)-
CAS No.	868163-15-9
Molecular Formula	C9H7ClO2
Molecular Weight	182.60 g/mol
Synonyms	(2E)-3-(3-Hydroxyphenyl)prop-2-enoyl chloride; 3-(3-Hydroxyphenyl)-(2E)-propenoyl chloride; (E)-3-(3-Hydroxyphenyl)acryloyl chloride; trans-3-(3-Hydroxyphenyl)acryloyl chloride; 3'-Hydroxycinnamoyl chloride, (E)-; m-Hydroxycinnamoyl chloride; 868163-15-9
EINECS	Contact for details

Quality Control

Every batch of 2-Propenoyl Chloride, 3-(3-Hydroxyphenyl)-, (2E)- is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and batch-to-batch consistency through advanced techniques like HPLC, GC, and NMR. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at temperatures between 2°C and 8°C (refrigerated) to maximize stability due to its highly volatile and hygroscopic nature. Keep away from heat, sparks, open flames, strong bases, and oxidizing agents. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.