Description

Udp-6-Azido-6-Deoxy-D-Galactose Disodium Salt is a specialized nucleotide sugar derivative, a crucial biochemical tool for metabolic glycoengineering and glycobiology research. This compound serves as a key metabolic precursor, enabling the site-specific incorporation of azido-modified galactose residues into cellular glycans via the salvage pathway. It is primarily utilized by researchers and developers in pharmaceutical R&D, biotechnology, and academic laboratories for applications such as cell surface labeling, glycan profiling, and the development of novel bioconjugation strategies.

Application

• Metabolic Glycoengineering (MGE): Acts as a biosynthetic precursor for the metabolic labeling of cell surface glycans with azide functional groups for subsequent bioorthogonal click chemistry.
• Glycobiology Research: Used to study galactose metabolism, glycosylation pathways, and the function of specific glycoconjugates in cellular processes.
• Bioconjugation & Drug Delivery: Enables the chemoselective attachment of probes, drugs, or nanoparticles to labeled glycoproteins or glycolipids for targeted delivery and imaging.
• Diagnostic Probe Development: Facilitates the creation of novel tools for detecting and imaging specific glycosylation patterns associated with diseases like cancer.
• Enzymatic Synthesis: Serves as a substrate for glycosyltransferases in the enzymatic synthesis of complex oligosaccharides or glycoconjugates.
• Cell Surface Engineering: Used to remodel cell surface glycans to alter cell-cell interactions, immune recognition, or viral entry mechanisms.

Basic Information

Product Name	Udp-6-Azido-6-Deoxy-D-Galactose Disodium Salt
CAS No.	868141-12-2
Molecular Formula	C15H21N5Na2O16P2
Molecular Weight	635.27 g/mol
Synonyms	UDP-6-N3-Gal; UDP-6-Azidogalactose disodium salt; Uridine 5'-(trihydrogen diphosphate) P'→5'-ester with 6-azido-6-deoxy-D-galactose, disodium salt; 6-Azido-6-deoxy-D-galactose UDP disodium salt; UDP-α-D-6-azidogalactose disodium; UDP-GalNAz analogue; Uridine diphosphate 6-azidogalactose disodium salt
EINECS	Contact for details

Quality Control

Our Udp-6-Azido-6-Deoxy-D-Galactose Disodium Salt is manufactured under controlled conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to stringent in-house quality standards to guarantee product integrity. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Endotoxin	< 10 EU/mg (if applicable)
Biological Activity	Functional in cell-based MGE assays

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.