Description

3-(Difluoromethoxy)Phenylisothiocyanate is a specialized aromatic isothiocyanate building block featuring a difluoromethoxy substituent. This compound is valued for its role as a key intermediate in the synthesis of advanced heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the bioactivity of the isothiocyanate and difluoromethoxy groups.
• Chemical Research: Serves as a versatile reagent in organic synthesis for constructing complex sulfur- and fluorine-containing heterocycles.
• Material Science: Potential precursor for specialty polymers and advanced materials requiring specific fluorine functionalities.

Basic Information

Product Name	3-(Difluoromethoxy)Phenylisothiocyanate
CAS No.	865149-70-8
Molecular Formula	C8H5F2NOS
Molecular Weight	201.19 g/mol
Synonyms	3-(Difluoromethoxy)phenyl isothiocyanate; 1-Isothiocyanato-3-(difluoromethoxy)benzene; [3-(Difluoromethoxy)phenyl] isothiocyanate; m-(Difluoromethoxy)phenyl isothiocyanate; 3-Difluoromethoxyphenyl isothiocyanate; Benzene, 1-isothiocyanato-3-(difluoromethoxy)-; Isocyanic acid, 3-(difluoromethoxy)phenyl ester
EINECS	Contact for details

Quality Control

Our 3-(Difluoromethoxy)Phenylisothiocyanate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.