Description

1-Methyl-3-Phenyl-1H-Pyrazole-5-Carbonyl Chloride is a versatile and highly reactive acyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to efficiently introduce the 1-methyl-3-phenylpyrazole-5-carbonyl moiety, a privileged scaffold in medicinal chemistry, into target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing the pyrazole heterocycle.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
• Material Science Research: Employed in the development of specialty polymers, ligands, and functional materials.
• Peptide Mimetics & Bioconjugation: Acts as an acylating agent for modifying peptides or creating peptide-like structures.
• Chemical Biology Probes: Useful for labeling biomolecules or creating tool compounds for target identification and validation.
• Custom Synthesis & Contract Manufacturing: A high-value intermediate for custom synthesis projects and scale-up services.

Basic Information

Product Name	1-Methyl-3-Phenyl-1H-Pyrazole-5-Carbonyl Chloride
CAS No.	864068-95-1
Molecular Formula	C11H9ClN2O
Molecular Weight	220.66 g/mol
Synonyms	1-Methyl-3-phenyl-1H-pyrazole-5-carbonyl chloride; 1-Methyl-3-phenylpyrazole-5-carbonyl chloride; 5-(Chlorocarbonyl)-1-methyl-3-phenyl-1H-pyrazole; 1-Methyl-3-phenyl-1H-pyrazole-5-carboxylic acid chloride; 864068-95-1; 1-Methyl-3-phenylpyrazole-5-carboxylic acid chloride; 3-Phenyl-1-methyl-1H-pyrazole-5-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-3-Phenyl-1H-Pyrazole-5-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.