Description

cis-4-Azidocyclohexane Carboxylic Acid is a versatile bifunctional organic building block featuring both a carboxylic acid and an azide functional group on a cyclohexane scaffold. This compound is of significant value in medicinal chemistry and materials science for its utility in click chemistry reactions, particularly the copper-catalyzed azide-alkyne cycloaddition (CuAAC). It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel drug candidates, bioconjugates, and advanced polymeric materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor for the synthesis of bioactive molecules and potential drug candidates via click chemistry.
• Bioconjugation Linker: Used to attach small molecules, peptides, or fluorescent tags to proteins, antibodies, or other biomolecules.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for creating functional polymers, hydrogels, and dendrimers with tailored properties.
• Chemical Probe Development: Enables the creation of activity-based probes for studying enzyme function and biological pathways.
• Material Science: Incorporated into surface coatings and nanomaterials to introduce specific chemical functionalities.
• Peptidomimetics: Used in the design and synthesis of cyclic peptide analogs and conformationally constrained scaffolds.

Basic Information

Product Name	cis-4-Azidocyclohexane Carboxylic Acid
CAS No.	863222-21-3
Molecular Formula	C7H11N3O2
Molecular Weight	169.18 g/mol
Synonyms	4-Azidocyclohexanecarboxylic acid, cis-; cis-4-Azidocyclohexanecarboxylic acid; (1r,4r)-4-Azidocyclohexanecarboxylic acid; 4-Azidocyclohexane-1-carboxylic acid; Azidocyclohexanecarboxylic acid; Cyclohexanecarboxylic acid, 4-azido-, cis-; 863222-21-3; (1R,4R)-4-Azidocyclohexane-1-carboxylic Acid
EINECS	Contact for details

Quality Control

Our cis-4-Azidocyclohexane Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your research and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and potential for oxidation, it is recommended to store the material under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.