Description

5-(5-Ethyl-2-Thienyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride is a high-value, multifunctional chemical building block designed for advanced synthetic applications. Its core value lies in its reactive carbonyl chloride group and complex heterocyclic structure, enabling the precise construction of novel molecular frameworks. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on creating new active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Research: Serves as a critical building block for developing next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Used in the research of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to its electron-deficient pyrimidine core.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry for studying protein interactions and developing diagnostic tools.
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	5-(5-Ethyl-2-Thienyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride
CAS No.	863190-20-9
Molecular Formula	C14H9ClF3N3OS
Molecular Weight	383.75 g/mol
Synonyms	5-(5-Ethyl-2-thienyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; 863190-20-9; Pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 5-(5-ethyl-2-thienyl)-7-(trifluoromethyl)-; 5-(5-Ethylthiophen-2-yl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-(5-Ethyl-2-Thienyl)-7-(Trifluoromethyl)Pyrazolo[1,5-A]Pyrimidine-2-Carbonyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency that meet the exacting standards of advanced R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.