Description

Azilsartan Medoxomil is a potent, selective angiotensin II receptor blocker (ARB) prodrug used as an active pharmaceutical ingredient (API). It is a key therapeutic agent in the management of hypertension, offering effective blood pressure control. This high-purity compound is essential for pharmaceutical manufacturers developing finished dosage forms, such as tablets, for the global cardiovascular drug market. Azilsartan Medoxomil CAS NO 863031-21-4 represents a critical component in modern antihypertensive therapy.

Application

• Primary Pharmaceutical Ingredient: Manufacture of antihypertensive medications, primarily in tablet formulations.
• Hypertension Treatment: Core API in drugs prescribed for the management of essential hypertension in adult patients.
• Cardiovascular Drug Development: Used in R&D for new and generic drug formulations targeting the renin-angiotensin system.
• Clinical Trial Material: Serves as the active component in clinical supplies for Phase I-IV studies.
• Reference Standard: High-purity grade suitable for use as an analytical reference standard in quality control laboratories.
• Combination Therapies: Potential use in fixed-dose combination products with other antihypertensive agents like chlorthalidone.

Basic Information

Product Name	Azilsartan Medoxomil
CAS No.	863031-21-4
Molecular Formula	C30H24N4O8
Molecular Weight	568.53 g/mol
Synonyms	TAK-491; Azilsartan Kamedoxomil; (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-ethoxy-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate; Edarbi (Brand Name); Azilsartan Medoxomil Potassium; TAK-536
EINECS	Contact for details

Quality Control

Our Azilsartan Medoxomil is manufactured under strict quality systems to meet the stringent requirements of the global pharmaceutical industry. Production adheres to current Good Manufacturing Practices (cGMP) and is supported by a comprehensive analytical control strategy. Each batch is tested against rigorous specifications for identity, purity, and potency. A detailed Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.