Description

7-Difluoromethyl-5-(2-Methoxy-Phenyl)-Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride is a high-value, multi-functional heterocyclic building block and key synthetic intermediate. Its molecular structure, featuring a reactive acid chloride group and a difluoromethyl substituent, makes it a critical precursor for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the difluoromethyl group for enhanced bioactivity and metabolic stability.
• Material Science Research: Acts as a precursor for creating specialized polymers or organic electronic materials with unique fluorinated properties.
• Chemical Biology Probes: Utilized in the development of fluorescent tags or activity-based probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	7-Difluoromethyl-5-(2-Methoxy-Phenyl)-Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride
CAS No.	862705-28-0
Molecular Formula	C15H10ClF2N3O2
Molecular Weight	337.71 g/mol
Synonyms	7-(Difluoromethyl)-5-(2-methoxyphenyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride; 5-(2-Methoxyphenyl)-7-(difluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride; Pyrazolo[1,5-a]pyrimidine-3-carbonyl chloride, 7-(difluoromethyl)-5-(2-methoxyphenyl)-; 862705-28-0; 7-Difluoromethyl-5-(2-Methoxy-Phenyl)-Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride
EINECS	Contact for details

Quality Control

Our 7-Difluoromethyl-5-(2-Methoxy-Phenyl)-Pyrazolo[1,5-A]Pyrimidine-3-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as an acid chloride, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation from moisture. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.