Description

5-Cyclopropyl-7-Trifluoromethyl-Pyrazolo[1,5-A]-Pyrimidine-2-Carbonyl Chloride is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, offering a versatile scaffold for structure-activity relationship (SAR) studies. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating next-generation products.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Biology Probe Development: Serves as a core structure for creating molecular probes to study biological pathways and target validation.
• Material Science Research: Potential precursor for the synthesis of specialty polymers or organic electronic materials with unique properties.
• Custom Synthesis & Contract Manufacturing: Essential reagent for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	5-Cyclopropyl-7-Trifluoromethyl-Pyrazolo[1,5-A]-Pyrimidine-2-Carbonyl Chloride
CAS No.	861452-42-8
Molecular Formula	C11H7ClF3N3O
Molecular Weight	289.64 g/mol
Synonyms	5-Cyclopropyl-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; 5-Cyclopropyl-7-trifluoromethylpyrazolo[1,5-a]pyrimidine-2-carbonyl chloride; Pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride, 5-cyclopropyl-7-(trifluoromethyl)-; 861452-42-8; 5-Cyclopropyl-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 5-Cyclopropyl-7-Trifluoromethyl-Pyrazolo[1,5-A]-Pyrimidine-2-Carbonyl Chloride adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications and supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.