Description

Ethyl 2-Isothiocyanato-5-Methyl-4-Phenylthiophene-3-Carboxylate is a specialized heterocyclic building block featuring both an isothiocyanate and an ester functional group on a thiophene core. This compound is valued for its role as a versatile synthetic intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting specific biological pathways.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, such as herbicides and fungicides.
• Chemical Biology Probe Synthesis: The reactive isothiocyanate group allows for conjugation with biomolecules, useful in creating probes for studying biological systems.
• Material Science: Acts as a monomer or functionalizing agent in the development of advanced polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploratory synthesis projects.

Basic Information

Product Name	Ethyl 2-Isothiocyanato-5-Methyl-4-Phenylthiophene-3-Carboxylate
CAS No.	861239-52-3
Molecular Formula	C15H13NO2S2
Molecular Weight	303.40 g/mol
Synonyms	Ethyl 5-methyl-4-phenyl-2-isothiocyanatothiophene-3-carboxylate; 2-Isothiocyanato-5-methyl-4-phenylthiophene-3-carboxylic acid ethyl ester; 4-Phenyl-5-methylthiophene-3-carboxylic acid ethyl ester 2-isothiocyanate; Thiophene-3-carboxylic acid, 2-isothiocyanato-5-methyl-4-phenyl-, ethyl ester
EINECS	Contact for details

Quality Control

Our production of Ethyl 2-Isothiocyanato-5-Methyl-4-Phenylthiophene-3-Carboxylate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and analyzed using modern spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.