Description

2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride is a specialized organic intermediate featuring a reactive acid chloride group, making it a valuable building block for the synthesis of more complex quinoline derivatives. This compound is critical for research and development in advanced material science and pharmaceutical chemistry, where precise molecular construction is paramount. It is primarily sought after by fine chemical manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors and other biologically active quinoline-based molecules.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the quinoline scaffold can contribute to specific modes of action.
• Material Science Research: Serves as a precursor for creating functionalized organic ligands used in metal-organic frameworks (MOFs) or as components in organic electronic materials.
• Dye and Pigment Intermediate: Employed in the synthesis of complex heterocyclic dyes and pigments for high-performance applications.
• Chemical Biology Probes: Utilized to develop fluorescent tags or affinity probes for studying biological processes, leveraging the quinoline structure's properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the global fine chemical market.

Basic Information

Product Name	2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride
CAS No.	860112-78-3
Molecular Formula	C17H12ClNO
Molecular Weight	281.74 g/mol
Synonyms	2-(p-Tolyl)quinoline-4-carbonyl chloride; 4-Quinolinecarbonyl chloride, 2-(4-methylphenyl)-; 2-(4-Methylphenyl)-4-quinolinecarbonyl chloride; p-Tolylquinoline-4-carbonyl chloride; 2-(4-Methylphenyl)quinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-(4-Methylphenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.