Description

2-Thiazoline-2-Acetyl Chloride (5Ci) is a specialized organosulfur reagent featuring a highly reactive acid chloride functional group. This compound is critical for the efficient synthesis of amide and ester derivatives, enabling the introduction of the 2-thiazoline moiety into complex molecular architectures. It serves as a key building block for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly those targeting infectious diseases or metabolic disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the thiazoline ring contributes to biological activity.
• Peptide Mimetics & Conjugation: Facilitates the creation of peptide analogs and bioconjugates for biochemical research and diagnostic applications.
• Material Science Research: Employed in the development of functional polymers and ligands for catalysis or metal ion chelation.
• Chemical Biology Probes: Serves as a reagent for labeling or modifying biomolecules to study biological pathways and interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Thiazoline-2-Acetyl Chloride (5Ci)
CAS No.	859486-04-7
Molecular Formula	C5H6ClNOS
Molecular Weight	163.62 g/mol
Synonyms	2-(Chloroacetyl)thiazoline; 2-Thiazolineacetyl chloride; 2-(2-Thiazolinyl)acetyl chloride; (2-Thiazolin-2-yl)acetyl chloride; 2-Thiazoline-2-acetic acid chloride; 2-(Chloroacetyl)-2-thiazoline; 2-Thiazolylacetyl chloride (related); NSC 405124
EINECS	Contact for details

Quality Control

Every batch of 2-Thiazoline-2-Acetyl Chloride (5Ci) is manufactured and tested under strict quality management protocols. We provide comprehensive analytical data to ensure product identity, purity, and consistency for your critical research and development processes. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting key parameters such as assay and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.