Description

γ-Hydroxy-α,α-Dimethylbutyryl Chloride Acetate is a specialized organic acid chloride derivative, serving as a critical high-purity building block in advanced chemical synthesis. Its reactive acyl chloride group makes it an essential reagent for introducing the γ-hydroxy-α,α-dimethylbutyryl moiety, enabling precise molecular construction. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and fine chemical sectors for developing active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex ester or amide linkages.
• Peptide & Protein Modification: Used as an acylating agent to modify amino acid side chains or peptide termini, introducing specific functional groups for biochemical research.
• Polymer Chemistry: Acts as a monomer or cross-linking agent in the production of specialty polymers with tailored properties, such as biodegradable materials or drug delivery systems.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex natural product analogs and other high-value specialty chemicals.
• Agrochemical Research: Utilized in the development of advanced pesticide and herbicide molecules, where its specific structure can contribute to biological activity.
• Material Science: Serves as a precursor for surface functionalization of materials, creating specific chemical interfaces for advanced coatings or composites.

Basic Information

Item	Details
Product Name	γ-Hydroxy-α,α-Dimethylbutyryl Chloride Acetate
CAS No.	859082-28-3
Molecular Formula	C8H13ClO3
Molecular Weight	192.64 g/mol
Synonyms	4-Hydroxy-2,2-dimethylbutyryl chloride acetate; 2,2-Dimethyl-4-hydroxybutyryl chloride acetate; Acetic acid, (4-chloro-3-hydroxy-3-methyl-1-oxobutyl) ester; γ-Hydroxy-α,α-dimethylbutyroyl chloride acetate; 3-Methyl-3-hydroxybutyryl chloride acetate (related isomer); HDMBCA; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our γ-Hydroxy-α,α-Dimethylbutyryl Chloride Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We adhere to cGMP principles where applicable to support our clients in regulated development pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.