Description

11,12-Di-o-Acetyltenacigenin B is a specific, high-purity derivative of the natural product tenacigenin B, characterized by the acetylation of its hydroxyl groups at the 11 and 12 positions. This compound is of significant interest in advanced pharmaceutical research and development due to its potential as a key intermediate or reference standard for bioactive natural product derivatives. It is primarily utilized by research institutions, pharmaceutical companies, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis and study of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathways for novel drug candidates, particularly in oncology and metabolic disease research.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in HPLC and LC-MS analysis of tenacigenin derivatives.
• Biochemical Research: Employed in in vitro studies to investigate structure-activity relationships (SAR) and biological mechanisms of natural product analogs.
• Process Chemistry Development: Acts as a model compound for scaling up synthetic routes and optimizing reaction conditions in pilot-scale manufacturing.

Basic Information

Product Name	11,12-Di-o-Acetyltenacigenin B
CAS No.	857897-01-9
Molecular Formula	C29H38O8
Molecular Weight	514.61 g/mol
Synonyms	11,12-Di-O-acetyltenacigenin B; Tenacigenin B 11,12-diacetate; (3β,5α,8β,9α,11α,12β,14β,17α)-3,14-Dihydroxy-11,12-bis(acetyloxy)-4,4,8,10,14-pentamethyl-17-[(2E)-2-methylbut-2-enoyl]oxy]gonane-2,15-dione; 11β,12β-Diacetoxy-3β,14β-dihydroxy-17α-(2-methyl-2-butenoyloxy)-5α,8β,9α,10α,13α,14β,17αH,18βH,19αH-pregna-2,15-dione
EINECS	Contact for details

Quality Control

Our 11,12-Di-o-Acetyltenacigenin B is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.