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1,3,4,6-Tetra-o-Acetyl-2-Deoxy-2-[(2-Azidoacetyl)Amino]-β-D-Glucopyranose CAS NO 857677-98-6
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CAS No.:857677-98-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1,3,4,6-Tetra-o-Acetyl-2-Deoxy-2-[(2-Azidoacetyl)Amino]-β-D-Glucopyranose is a sophisticated, high-purity carbohydrate derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique structure, featuring both acetyl-protected hydroxyl groups and an azidoacetyl-modified amino group, making it an essential precursor for the development of complex glycoconjugates and bioactive molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in carbohydrate chemistry, medicinal chemistry, and the synthesis of novel glycopeptide antibiotics or vaccine adjuvants.
Application
- Glycopeptide & Glycoprotein Synthesis: A key glycosyl donor or acceptor intermediate for constructing complex oligosaccharide chains in drug discovery.
- Medicinal Chemistry Research: Used as a scaffold for developing new antimicrobial agents, particularly against resistant bacterial strains.
- Bioconjugation & Click Chemistry: The azido group enables efficient, site-specific conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for labeling or linking biomolecules.
- Carbohydrate Mimetics Development: Serves as a starting material for creating glycomimetics that modulate biological recognition processes.
- Antiviral & Anticancer Agent Research: Investigated as a precursor for novel nucleoside analogs or cell-surface glycan-targeting therapeutics.
- Chemical Biology Probes: Utilized to synthesize activity-based probes for studying glycosidase enzymes or carbohydrate-processing pathways.
Basic Information
| Product Name | 1,3,4,6-Tetra-o-Acetyl-2-Deoxy-2-[(2-Azidoacetyl)Amino]-β-D-Glucopyranose |
| CAS No. | 857677-98-6 |
| Molecular Formula | C16H22N4O10 |
| Molecular Weight | 430.37 g/mol |
| Synonyms | 2-Deoxy-2-[(2-azidoacetamido)]-D-glucopyranose tetraacetate; 2-Azidoacetamido-2-deoxy-D-glucose tetraacetate; N-(2-Azidoacetyl)-D-glucosamine tetraacetate; 1,3,4,6-Tetra-O-acetyl-2-deoxy-2-(2-azidoacetamido)-β-D-glucopyranose; β-D-Glucopyranose, 2-(azidoacetamido)-1,3,4,6-tetra-O-acetyl-2-deoxy-; GlcNAc(Ac)4-N3Ac; Azidoacetyl-glucosamine tetraacetate |
| EINECS | Contact for details |
Quality Control
Our production of 1,3,4,6-Tetra-o-Acetyl-2-Deoxy-2-[(2-Azidoacetyl)Amino]-β-D-Glucopyranose adheres to stringent quality protocols suitable for research and pharmaceutical intermediate applications. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided, detailing results from HPLC, NMR, and mass spectrometry. We support compliance with relevant research and development standards, and specifications can be tailored to meet specific project requirements.
Storage
Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, well-ventilated area. This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Specific Rotation | Contact for details |
| Water Content (KF) | ≤ 0.5% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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