Description

Benzo[B]Furan-3-Ylacetyl Chloride is a high-purity, reactive acyl chloride derivative used as a critical building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients and functional materials. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the benzo[b]furan-3-ylacetyl moiety into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging the benzo[b]furan scaffold for bioactivity.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers and advanced organic materials.
• Chemical Biology Probes: Employed to create labeled compounds or activity-based probes for studying enzyme function and biological mechanisms.
• Ligand Synthesis for Catalysis: Facilitates the preparation of complex ligands used in asymmetric catalysis and transition metal complexes.

Basic Information

Product Name	Benzo[B]Furan-3-Ylacetyl Chloride
CAS No.	857283-98-8
Molecular Formula	C₁₂H₉ClO₂
Molecular Weight	220.65 g/mol
Synonyms	2-(Benzofuran-3-yl)acetyl chloride; 3-Benzofuranylacetyl chloride; 2-(1-Benzofuran-3-yl)acetyl chloride; 1-Benzofuran-3-acetyl chloride; (Benzofuran-3-yl)acetyl chloride; 3-Benzofurylacetyl chloride; 2-(Benzo[b]furan-3-yl)acetyl chloride; α-Oxo-1-benzofuran-3-acetyl chloride
EINECS	Contact for details

Quality Control

Our Benzo[B]Furan-3-Ylacetyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.