Description

Cediranib Maleate CAS NO 857036-77-2 is a potent and selective small-molecule inhibitor targeting vascular endothelial growth factor receptors (VEGFRs). This compound is of significant value in pharmaceutical research and development, particularly in the field of oncology. It is primarily needed by research institutions, pharmaceutical companies, and contract research organizations (CROs) engaged in the discovery and development of novel anti-cancer therapeutics.

Application

• Pharmaceutical R&D: Serves as a critical reference standard and active pharmaceutical ingredient (API) in the development of anti-angiogenic cancer therapies.
• Biochemical Research: Used as a selective VEGFR inhibitor in cell-based assays and enzymatic studies to investigate angiogenesis signaling pathways.
• Preclinical Studies: Employed in animal models to evaluate the efficacy, pharmacokinetics, and toxicity profiles of VEGFR-targeted treatments.
• Analytical Standard: Functions as a high-purity standard for quality control and method validation in HPLC, LC-MS, and other analytical techniques.

Basic Information

Product Name	Cediranib Maleate
CAS No.	857036-77-2
Molecular Formula	C₂₅H₂₇FN₄O₃ • C₄H₄O₄
Molecular Weight	563.57 g/mol
Synonyms	AZD2171 Maleate; Recentin; 4-[(4-Fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline maleate; Cediranib (AZD2171) Maleate; UNII-6M3C4ZY4XE; (Z)-But-2-enedioic acid;4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline
EINECS	Contact for details

Quality Control

Our Cediranib Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, MS) to ensure it meets high-grade standards suitable for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.