Description

Tedizolid Phosphate is a second-generation oxazolidinone antibiotic prodrug, representing a significant advancement in the treatment of serious Gram-positive bacterial infections. Its primary value lies in its enhanced potency, favorable safety profile, and convenient once-daily dosing regimen compared to earlier agents in its class. This high-purity active pharmaceutical ingredient (API) is essential for pharmaceutical manufacturers developing and producing next-generation antibacterial formulations, particularly for hospital-acquired and community-acquired infections.

Application

• Pharmaceutical API Manufacturing: Primary use as the active ingredient in the synthesis of finished dosage forms, such as tablets and intravenous solutions.
• Antibacterial Drug Development: Critical raw material for R&D and clinical trials of new antibacterial therapies targeting resistant pathogens.
• Treatment of Acute Bacterial Skin and Skin Structure Infections (ABSSSI): Formulation into medications specifically indicated for complicated skin infections.
• Hospital-Use Injectable Formulations: Production of sterile injectable products for the treatment of severe infections in clinical settings.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.
• Combination Therapy Research: Used in studies exploring synergistic effects with other antimicrobial agents.

Basic Information

Product Name	Tedizolid Phosphate
CAS No.	856867-55-5
Molecular Formula	C17H20FN6O6P
Molecular Weight	454.35 g/mol
Synonyms	TR-701 FA; Tedizolid Phosphate (USP); (R)-3-(4-(2-(2-Methyltetrazol-5-yl)pyridin-5-yl)-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one phosphate; Torezolid phosphate; DA-7217; Sivextro (Brand Name); (R)-3-(3-Fluoro-4-(6-(2-methyl-2H-tetrazol-5-yl)pyridin-3-yl)phenyl)-5-(hydroxymethyl)oxazolidin-2-one phosphate
EINECS	Contact for details

Quality Control

Our Tedizolid Phosphate is manufactured under strict quality management systems, targeting compliance with USP and ICH guidelines. Every batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and stringent control of related substances and residual solvents. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure full traceability and regulatory support for your pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	≤ 20 ppm
Specific Rotation	+17.0° to +20.0° (c=1, in DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.