Description

(3R,5S)-5-((R)-8-Fluoro-4-Isopropyl-2-(n-Methylmethylsulfonam Ido)-5,6-Dihydrobenzo[H]Quinazolin-6-Yl)-3,5-Dihydroxypentanoate Calcium(Ii) CAS NO 854898-49-0 is a high-purity, complex calcium salt of a dihydroxypentanoate derivative, designed for advanced pharmaceutical research and development. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) or reference standard in the synthesis of novel therapeutic agents, particularly those targeting specific enzymatic pathways. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, high-quality building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for complex small-molecule drugs.
• Drug Discovery & Research: Used as a reference standard or precursor in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Analytical Reference Standard: Serves as a high-purity calibrant for method development and quality control in HPLC, LC-MS, and NMR analysis.
• Biochemical Research: Potential use in studying enzyme inhibition or modulation due to its specific quinazolin-based structure.
• Custom Synthesis: Starting material for the preparation of more complex derivatives and analogs for specialized research programs.

Basic Information

Item	Details
Product Name	(3R,5S)-5-((R)-8-Fluoro-4-Isopropyl-2-(n-Methylmethylsulfonam Ido)-5,6-Dihydrobenzo[H]Quinazolin-6-Yl)-3,5-Dihydroxypentanoate Calcium(Ii)
CAS No.	854898-49-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Calcium (3R,5S)-5-((R)-8-fluoro-4-isopropyl-2-(N-methylmethylsulfonamido)-5,6-dihydrobenzo[h]quinazolin-6-yl)-3,5-dihydroxypentanoate; 854898-49-0; Calcium salt of (3R,5S)-dihydroxypentanoate derivative; Fluorinated quinazolin calcium complex; Dihydrobenzo[h]quinazolin calcium intermediate; N-Methylmethanesulfonamide quinazolin calcium salt; Advanced fluorinated API intermediate.
EINECS	Contact for details

Quality Control

Our (3R,5S)-5-((R)-8-Fluoro-4-Isopropyl-2-(n-Methylmethylsulfonam Ido)-5,6-Dihydrobenzo[H]Quinazolin-6-Yl)-3,5-Dihydroxypentanoate Calcium(Ii) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Ensure the storage area is well-ventilated and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	Contact for details
Heavy Metals	< 10 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.