Description

2-(3,4-Dichlorophenyl)Quinoline-4-Carbonyl Chloride is a high-value, reactive organic intermediate characterized by its quinoline core and acid chloride functionality. This compound is essential for the synthesis of advanced pharmaceutical agents and agrochemicals, where it serves as a key building block for introducing the 2-(3,4-dichlorophenyl)quinoline moiety. It is primarily sought after by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used to construct advanced fungicides, herbicides, and insecticides, leveraging the bioactivity of the dichlorophenyl-quinoline structure.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of organic electronic materials, such as OLEDs and sensors.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(3,4-Dichlorophenyl)Quinoline-4-Carbonyl Chloride
CAS No.	854863-97-1
Molecular Formula	C₁₆H₈Cl₃NO
Molecular Weight	336.60 g/mol
Synonyms	4-Quinolinecarbonyl chloride, 2-(3,4-dichlorophenyl)-; 2-(3,4-Dichlorophenyl)-4-quinolinecarbonyl chloride; 2-(3,4-Dichlorophenyl)quinoline-4-carboxylic acid chloride; 854863-97-1; Quinoline-4-carbonyl chloride, 2-(3,4-dichlorophenyl)-; 2-(3,4-DCP)quinoline-4-COCl
EINECS	Contact for details

Quality Control

Our production of 2-(3,4-Dichlorophenyl)Quinoline-4-Carbonyl Chloride adheres to stringent in-process and final quality controls to ensure batch-to-batch consistency and high purity. Quality is verified via advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We operate under a quality management system and can support development projects requiring ICH stability studies or GMP-grade material upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.