Description

8-Methyl-2-Phenylquinoline-4-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in the development of complex heterocyclic molecules, particularly in pharmaceutical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides with quinoline core structures.
• Material Science: Serves as a monomer or functionalization agent for creating specialty polymers and advanced organic materials.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Fluorescent Dye & Sensor Development: Acts as a foundational structure for synthesizing new fluorescent probes and chemosensors.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological studies and novel compound library generation.

Basic Information

Product Name	8-Methyl-2-Phenylquinoline-4-Carbonyl Chloride
CAS No.	854863-92-6
Molecular Formula	C18H12ClNO
Molecular Weight	293.75 g/mol
Synonyms	2-Phenyl-8-methylquinoline-4-carbonyl chloride; 8-Methyl-2-phenyl-4-quinolinecarbonyl chloride; 4-Quinolinecarbonyl chloride, 8-methyl-2-phenyl-; 8-Methyl-2-phenylquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 8-Methyl-2-Phenylquinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.