Description

Bms 354825 Hydrochloride is a high-purity, small-molecule chemical compound used as a critical intermediate and reference standard in advanced research and development. This compound is valued for its precise chemical structure and consistent performance in demanding synthesis and analytical workflows. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on drug discovery and biochemical pathway analysis.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of novel therapeutic agents and as a reference standard for analytical method development and validation.
• Biochemical Research: Used as a selective inhibitor or modulator in enzymatic and cellular assays to study specific biological pathways and protein functions.
• Analytical Chemistry: Employed as a certified reference material (CRM) for calibrating instruments like HPLC and LC-MS, ensuring accurate quantification in complex matrices.
• Preclinical Studies: Utilized in in vitro and in vivo studies to investigate pharmacokinetics, pharmacodynamics, and initial safety profiles of drug candidates.
• Chemical Synthesis: Acts as a sophisticated building block for constructing more complex molecular architectures in medicinal chemistry programs.

Basic Information

Product Name	Bms 354825 Hydrochloride
CAS No.	854001-07-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	BMS-354825 Hydrochloride; Dasatinib Hydrochloride (monohydrate form); Dasatinib HCl; BMS 354825 HCl; N-(2-Chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide monohydrochloride monohydrate; Sprycel (brand name reference); BMS354825 hydrochloride
EINECS	Contact for details

Quality Control

Our Bms 354825 Hydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	<20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.